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Link TCGA H&E imaging resources at slide level and add pathology metadata from GDC - #2354

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Link TCGA H&E imaging resources at slide level and add pathology metadata from GDC#2354
rmadupuri wants to merge 2 commits into
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update_tcga_resource

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@rmadupuri

@rmadupuri rmadupuri commented Aug 26, 2026

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Regenerated data_resource_patient.txt for all 32 TCGA Pan-Cancer Atlas 2018 studies.

Two changes:

  1. Slide microscopy is now linked per series instead of per study. IDC shows all H&E images in the SLIM viewer and hence one representative image was picked earlier. Since metadata is availble for each slide, all H&E seriesUIDs are pulled.
  2. A new METADATA column with tumor/necrosis/stromal percentages, immune infiltration, section location etc., is added

Radiology linking is unchanged: still one row per patient/study/modality, since OHIF loads the whole study.

METADATA format

JSON object per row/slide

{
  "slide_id": "2f52dd63-7476-4e85-b7c6-e06092db6cc1",
  "slide_submitter_id": "TCGA-3C-AAA",
  "section_location": "TOP",
  "percent_necrosis": 0,
  "percent_tumor_nuclei": 70,
  "percent_tumor_cells": 70,
  "percent_normal_cells": 0,
  "percent_stromal_cells": 30,
  "percent_lymphocyte_infiltration": 40,
  "percent_neutrophil_infiltration":
  "percent_monocyte_infiltration": 20
}

Source:
Metadata comes from the GDC /cases API joined to IDC via slide_submitter_id

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