protege-tutorial/basic-classification/ubiq-ligase-complex.owl at master · rfmatheus/protege-tutorial · GitHub

1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
703
704
705
706
707
708
709
710
711
712
713
714
715
716
717
718
719
720
721
722
723
724
725
726
727
728
729
730
731
732
733
734
735
736
737
738
739
740
741
742
743
744
745
746
747
748
749
750
751
752
753
754
755
756
757
758
759
760
761
762
763
764
765
766
767
768
769
770
771
772
773
774
775
776
777
778
779
780
781
782
783
784
785
786
787
788
789
790
791
792
793
794
795
796
797
798
799
800
801
802
803
804
805
806
807
808
809
810
811
812
813
814
815
816
817
818
819
820
821
822
823
824
825
826
827
828
829
830
831
832
833
834
835
836
837
838
839
840
841
842
843
844
845
846
847
848
849
850
851
852
853
854
855
856
857
858
859
860
861
862
863
864
865
866
867
868
869
870
871
872
873
874
875
876
877
878
879
880
881
882
883
884
885
886
887
888
889
890
891
892
893
894
895
896
897
898
899
900
901
902
903
904
905
906
907
908
909
910
911
912
913
914
915
916
917
918
919
920
921
922
923
924
925
926
927
928
929
930
931
932
933
934
935
936
937
938
939
940
941
942
943
944
945
946
947
948
949
950
951
952
953
954
955
956
957
958
959
960
961
962
963
964
965
966
967
968
969
970
971
972
973
974
975
976
977
978
979
980
981
982
983
984
985
986
987
988
989
990
991
992
993
994
995
996
997
998
999
1000
<?xml version="1.0"?>


<!DOCTYPE rdf:RDF [
    <!ENTITY owl "http://www.w3.org/2002/07/owl#" >
    <!ENTITY obo "http://purl.obolibrary.org/obo/" >
    <!ENTITY xsd "http://www.w3.org/2001/XMLSchema#" >
    <!ENTITY go "http://purl.obolibrary.org/obo/go#" >
    <!ENTITY rdfs "http://www.w3.org/2000/01/rdf-schema#" >
    <!ENTITY rdf "http://www.w3.org/1999/02/22-rdf-syntax-ns#" >
    <!ENTITY oboInOwl "http://www.geneontology.org/formats/oboInOwl#" >
]>


<rdf:RDF xmlns="&obo;go.owl#"
     xml:base="&obo;go.owl"
     xmlns:obo="http://purl.obolibrary.org/obo/"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:go="&obo;go#">
    <owl:Ontology rdf:about="&obo;go.owl">
        <oboInOwl:hasOBOFormatVersion rdf:datatype="&xsd;string">1.2</oboInOwl:hasOBOFormatVersion>
    </owl:Ontology>


    <!--
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <owl:AnnotationProperty rdf:about="&obo;go#systematic_synonym">
        <rdfs:label rdf:datatype="&xsd;string">Systematic synonym</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="&oboInOwl;SynonymTypeProperty"/>
        <oboInOwl:hasScope rdf:resource="&oboInOwl;hasExactSynonym"/>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&oboInOwl;shorthand">
        <rdfs:label rdf:datatype="&xsd;string">shorthand</rdfs:label>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&oboInOwl;inSubset">
        <rdfs:label rdf:datatype="&xsd;string">in_subset</rdfs:label>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&obo;go#mf_needs_review">
        <rdfs:comment rdf:datatype="&xsd;string">Catalytic activity terms in need of attention</rdfs:comment>
        <rdfs:subPropertyOf rdf:resource="&oboInOwl;SubsetProperty"/>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&oboInOwl;hasScope">
        <rdfs:label rdf:datatype="&xsd;string">has_scope</rdfs:label>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&oboInOwl;hasOBOFormatVersion">
        <rdfs:label rdf:datatype="&xsd;string">has_obo_format_version</rdfs:label>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&obo;IAO_0000115">
        <rdfs:label rdf:datatype="&xsd;string">definition</rdfs:label>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&oboInOwl;hasDbXref">
        <rdfs:label rdf:datatype="&xsd;string">database_cross_reference</rdfs:label>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&obo;go#goslim_generic">
        <rdfs:comment rdf:datatype="&xsd;string">Generic GO slim</rdfs:comment>
        <rdfs:subPropertyOf rdf:resource="&oboInOwl;SubsetProperty"/>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&obo;go#goslim_aspergillus">
        <rdfs:comment rdf:datatype="&xsd;string">Aspergillus GO slim</rdfs:comment>
        <rdfs:subPropertyOf rdf:resource="&oboInOwl;SubsetProperty"/>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&oboInOwl;hasAlternativeId">
        <rdfs:label rdf:datatype="&xsd;string">has_alternative_id</rdfs:label>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&obo;go#gosubset_prok">
        <rdfs:comment rdf:datatype="&xsd;string">Prokaryotic GO subset</rdfs:comment>
        <rdfs:subPropertyOf rdf:resource="&oboInOwl;SubsetProperty"/>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&oboInOwl;hasOBONamespace">
        <rdfs:label rdf:datatype="&xsd;string">has_obo_namespace</rdfs:label>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&oboInOwl;SubsetProperty">
        <rdfs:label rdf:datatype="&xsd;string">subset_property</rdfs:label>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&oboInOwl;id"/>
    <owl:AnnotationProperty rdf:about="&obo;go#goslim_pir">
        <rdfs:comment rdf:datatype="&xsd;string">PIR GO slim</rdfs:comment>
        <rdfs:subPropertyOf rdf:resource="&oboInOwl;SubsetProperty"/>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&oboInOwl;SynonymTypeProperty">
        <rdfs:label rdf:datatype="&xsd;string">synonym_type_property</rdfs:label>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&rdfs;label"/>
    <owl:AnnotationProperty rdf:about="&oboInOwl;hasExactSynonym">
        <rdfs:label rdf:datatype="&xsd;string">has_exact_synonym</rdfs:label>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&rdfs;comment"/>
    <owl:AnnotationProperty rdf:about="&obo;go#goslim_plant">
        <rdfs:comment rdf:datatype="&xsd;string">Plant GO slim</rdfs:comment>
        <rdfs:subPropertyOf rdf:resource="&oboInOwl;SubsetProperty"/>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&obo;go#goslim_candida">
        <rdfs:comment rdf:datatype="&xsd;string">Candida GO slim</rdfs:comment>
        <rdfs:subPropertyOf rdf:resource="&oboInOwl;SubsetProperty"/>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&oboInOwl;hasRelatedSynonym">
        <rdfs:label rdf:datatype="&xsd;string">has_related_synonym</rdfs:label>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&oboInOwl;hasNarrowSynonym">
        <rdfs:label rdf:datatype="&xsd;string">has_narrow_synonym</rdfs:label>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&obo;go#high_level_annotation_qc">
        <rdfs:comment rdf:datatype="&xsd;string">High-level terms not to be used for direct annotation</rdfs:comment>
        <rdfs:subPropertyOf rdf:resource="&oboInOwl;SubsetProperty"/>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&oboInOwl;hasBroadSynonym">
        <rdfs:label rdf:datatype="&xsd;string">has_broad_synonym</rdfs:label>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&obo;go#goslim_yeast">
        <rdfs:comment rdf:datatype="&xsd;string">Yeast GO slim</rdfs:comment>
        <rdfs:subPropertyOf rdf:resource="&oboInOwl;SubsetProperty"/>
    </owl:AnnotationProperty>
    <owl:AnnotationProperty rdf:about="&obo;go#goslim_pombe">
        <rdfs:comment rdf:datatype="&xsd;string">Fission yeast GO slim</rdfs:comment>
        <rdfs:subPropertyOf rdf:resource="&oboInOwl;SubsetProperty"/>
    </owl:AnnotationProperty>


    <!--
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->


    <!--
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->


    <!-- http://purl.obolibrary.org/obo/BFO_0000050 -->

    <owl:ObjectProperty rdf:about="&obo;BFO_0000050">
        <rdf:type rdf:resource="&owl;TransitiveProperty"/>
        <rdfs:label rdf:datatype="&xsd;string">part_of</rdfs:label>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">BFO:0000050</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">OBO_REL:part_of</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">gene_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:id rdf:datatype="&xsd;string">part_of</oboInOwl:id>
        <oboInOwl:shorthand rdf:datatype="&xsd;string">part_of</oboInOwl:shorthand>
    </owl:ObjectProperty>


    <!--
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->


    <!-- http://purl.obolibrary.org/obo/GO_0000151 -->

    <owl:Class rdf:about="&obo;GO_0000151">
        <rdfs:label rdf:datatype="&xsd;string">ubiquitin ligase complex</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0043234"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044424"/>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">A protein complex that includes a ubiquitin-protein ligase and other proteins that may confer substrate specificity on the complex.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0000151</oboInOwl:id>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_pir"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">A protein complex that includes a ubiquitin-protein ligase and other proteins that may confer substrate specificity on the complex.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:9529603</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0000151"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0000835 -->

    <owl:Class rdf:about="&obo;GO_0000835">
        <rdfs:label rdf:datatype="&xsd;string">ER ubiquitin ligase complex</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="&obo;GO_0000151"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="&obo;BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="&obo;GO_0005783"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="&obo;BFO_0000050"/>
                <owl:someValuesFrom rdf:resource="&obo;GO_0005789"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">A ubiquitin ligase complex found in the ER.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0000835</oboInOwl:id>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">A ubiquitin ligase complex found in the ER.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:elh</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0000835"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0005575 -->

    <owl:Class rdf:about="&obo;GO_0005575">
        <rdfs:label rdf:datatype="&xsd;string">cellular_component</rdfs:label>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0005575</oboInOwl:id>
        <oboInOwl:hasAlternativeId rdf:datatype="&xsd;string">GO:0008372</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">NIF_Subcellular:sao1337158144</oboInOwl:hasDbXref>
        <rdfs:comment rdf:datatype="&xsd;string">Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. Note that when this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code ND, no data, is used to indicate this.</rdfs:comment>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.</obo:IAO_0000115>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">cellular component</oboInOwl:hasExactSynonym>
        <oboInOwl:hasNarrowSynonym rdf:datatype="&xsd;string">cellular component unknown</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_aspergillus"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_candida"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_generic"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_pir"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_plant"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_yeast"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:go_curators</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0005575"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0005622 -->

    <owl:Class rdf:about="&obo;GO_0005622">
        <rdfs:label rdf:datatype="&xsd;string">intracellular</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044464"/>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0005622</oboInOwl:id>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.</obo:IAO_0000115>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">Wikipedia:Intracellular</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">internal to cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="&xsd;string">nucleocytoplasm</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">protoplasm</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="&xsd;string">protoplast</oboInOwl:hasRelatedSynonym>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_generic"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_pir"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_plant"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:mah</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">nucleocytoplasm</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0005622"/>
        <owl:annotatedProperty rdf:resource="&oboInOwl;hasRelatedSynonym"/>
    </owl:Axiom>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:mah</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">protoplast</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0005622"/>
        <owl:annotatedProperty rdf:resource="&oboInOwl;hasRelatedSynonym"/>
    </owl:Axiom>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">ISBN:0198506732</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0005622"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0005623 -->

    <owl:Class rdf:about="&obo;GO_0005623">
        <rdfs:label rdf:datatype="&xsd;string">cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0005575"/>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0005623</oboInOwl:id>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">NIF_Subcellular:sao1813327414</oboInOwl:hasDbXref>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.</obo:IAO_0000115>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">Wikipedia:Cell_(biology)</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_generic"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_plant"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:go_curators</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0005623"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0005634 -->

    <owl:Class rdf:about="&obo;GO_0005634">
        <rdfs:label rdf:datatype="&xsd;string">nucleus</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0043231"/>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell&#39;s chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0005634</oboInOwl:id>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">NIF_Subcellular:sao1702920020</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">Wikipedia:Cell_nucleus</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">cell nucleus</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_aspergillus"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_candida"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_generic"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_pir"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_plant"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_yeast"/>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell&#39;s chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:go_curators</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0005634"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0005680 -->

    <owl:Class rdf:about="&obo;GO_0005680">
        <rdfs:label rdf:datatype="&xsd;string">anaphase-promoting complex</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0000151"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0031461"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044428"/>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.</obo:IAO_0000115>
        <oboInOwl:hasBroadSynonym rdf:datatype="&xsd;string">APC</oboInOwl:hasBroadSynonym>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0005680</oboInOwl:id>
        <rdfs:comment rdf:datatype="&xsd;string">Note that the synonym &#39;APC&#39; should not be confused with the abbreviation for the adenomatous polyposis coli gene and protein.</rdfs:comment>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">Wikipedia:Anaphase-promoting_complex</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">anaphase promoting complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">cyclosome</oboInOwl:hasExactSynonym>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:jh</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:vw</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:10465783</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:10611969</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0005680"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0005737 -->

    <owl:Class rdf:about="&obo;GO_0005737">
        <rdfs:label rdf:datatype="&xsd;string">cytoplasm</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044424"/>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0005737</oboInOwl:id>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">Wikipedia:Cytoplasm</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_candida"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_generic"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_plant"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_yeast"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">ISBN:0198547684</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0005737"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0005783 -->

    <owl:Class rdf:about="&obo;GO_0005783">
        <rdfs:label rdf:datatype="&xsd;string">endoplasmic reticulum</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0043231"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044444"/>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">ER</oboInOwl:hasExactSynonym>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0005783</oboInOwl:id>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">NIF_Subcellular:sao1036339110</oboInOwl:hasDbXref>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).</obo:IAO_0000115>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">Wikipedia:Endoplasmic_reticulum</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_aspergillus"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_candida"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_generic"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_pir"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_plant"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_yeast"/>
    </owl:Class>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">ISBN:0198506732</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0005783"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0005789 -->

    <owl:Class rdf:about="&obo;GO_0005789">
        <rdfs:label rdf:datatype="&xsd;string">endoplasmic reticulum membrane</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0031090"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044425"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044432"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="&obo;BFO_0000050"/>
                <owl:someValuesFrom rdf:resource="&obo;GO_0042175"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">ER membrane</oboInOwl:hasExactSynonym>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0005789</oboInOwl:id>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">The lipid bilayer surrounding the endoplasmic reticulum.</obo:IAO_0000115>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
    </owl:Class>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:mah</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">The lipid bilayer surrounding the endoplasmic reticulum.</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0005789"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0012505 -->

    <owl:Class rdf:about="&obo;GO_0012505">
        <rdfs:label rdf:datatype="&xsd;string">endomembrane system</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044464"/>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0012505</oboInOwl:id>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">Wikipedia:Endomembrane_system</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_aspergillus"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_candida"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_yeast"/>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:lh</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0012505"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0016020 -->

    <owl:Class rdf:about="&obo;GO_0016020">
        <rdfs:label rdf:datatype="&xsd;string">membrane</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044464"/>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0016020</oboInOwl:id>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">Wikipedia:Biological_membrane</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_aspergillus"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_candida"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_pir"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_plant"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_yeast"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">Double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:mah</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">ISBN:0815316194</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0016020"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0019005 -->

    <owl:Class rdf:about="&obo;GO_0019005">
        <rdfs:label rdf:datatype="&xsd;string">SCF ubiquitin ligase complex</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0031461"/>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).</obo:IAO_0000115>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">CDL1 complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">CRL1 complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">Cul1-RING ubiquitin ligase complex</oboInOwl:hasExactSynonym>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0019005</oboInOwl:id>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">SCF complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasNarrowSynonym rdf:datatype="&xsd;string">SCF complex substrate recognition subunit</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">Skp1/Cul1/F-box protein complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">Wikipedia:SCF_complex</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">cullin-RING ligase 1</oboInOwl:hasExactSynonym>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:15571813</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:15688063</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0019005"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0030891 -->

    <owl:Class rdf:about="&obo;GO_0030891">
        <rdfs:label rdf:datatype="&xsd;string">VCB complex</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0000151"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044444"/>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0030891</oboInOwl:id>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">VHL complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">pVHL-elongin C-elongin B complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">von Hippel-Lindau tumor suppressor complex</oboInOwl:hasExactSynonym>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:mah</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:11865071</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0030891"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0031090 -->

    <owl:Class rdf:about="&obo;GO_0031090">
        <rdfs:label rdf:datatype="&xsd;string">organelle membrane</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0016020"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044422"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="&obo;BFO_0000050"/>
                <owl:someValuesFrom rdf:resource="&obo;GO_0043227"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0031090</oboInOwl:id>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">The lipid bilayer surrounding an organelle.</obo:IAO_0000115>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:mah</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">The lipid bilayer surrounding an organelle.</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0031090"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0031436 -->

    <owl:Class rdf:about="&obo;GO_0031436">
        <rdfs:label rdf:datatype="&xsd;string">BRCA1-BARD1 complex</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0000151"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044428"/>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0031436</oboInOwl:id>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:12787778</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0031436"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0031461 -->

    <owl:Class rdf:about="&obo;GO_0031461">
        <rdfs:label rdf:datatype="&xsd;string">cullin-RING ubiquitin ligase complex</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0000151"/>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity.</obo:IAO_0000115>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">CRL complex</oboInOwl:hasExactSynonym>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0031461</oboInOwl:id>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">cullin complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="&xsd;string">cullin-RING ligase</oboInOwl:hasRelatedSynonym>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:15571813</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:15688063</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0031461"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0032991 -->

    <owl:Class rdf:about="&obo;GO_0032991">
        <rdfs:label rdf:datatype="&xsd;string">macromolecular complex</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0005575"/>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0032991</oboInOwl:id>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">macromolecule complex</oboInOwl:hasExactSynonym>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_pir"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which the constituent parts function together.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:mah</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0032991"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0033768 -->

    <owl:Class rdf:about="&obo;GO_0033768">
        <rdfs:label rdf:datatype="&xsd;string">SUMO-targeted ubiquitin ligase complex</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0000151"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044428"/>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0033768</oboInOwl:id>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:vw</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:17762864</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:17762865</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0033768"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0042175 -->

    <owl:Class rdf:about="&obo;GO_0042175">
        <rdfs:label rdf:datatype="&xsd;string">nuclear outer membrane-endoplasmic reticulum membrane network</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0016020"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044425"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="&obo;BFO_0000050"/>
                <owl:someValuesFrom rdf:resource="&obo;GO_0012505"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0042175</oboInOwl:id>
        <oboInOwl:hasRelatedSynonym rdf:datatype="&xsd;string">NE-ER continuum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="&xsd;string">NE-ER network</oboInOwl:hasRelatedSynonym>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane.</obo:IAO_0000115>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym rdf:datatype="&xsd;string">nuclear envelope-ER network</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="&xsd;string">nuclear envelope-endoplasmic reticulum continuum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="&xsd;string">nuclear envelope-endoplasmic reticulum network</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">nuclear membrane-ER network</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">nuclear membrane-endoplasmic reticulum continuum</oboInOwl:hasExactSynonym>
    </owl:Class>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:mah</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">nuclear membrane-ER network</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0042175"/>
        <owl:annotatedProperty rdf:resource="&oboInOwl;hasExactSynonym"/>
    </owl:Axiom>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:mah</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">nuclear envelope-endoplasmic reticulum network</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0042175"/>
        <owl:annotatedProperty rdf:resource="&oboInOwl;hasRelatedSynonym"/>
    </owl:Axiom>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:bf</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:jl</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:mah</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:mcc</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:pr</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:vw</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane.</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0042175"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:mah</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">nuclear membrane-endoplasmic reticulum continuum</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0042175"/>
        <owl:annotatedProperty rdf:resource="&oboInOwl;hasExactSynonym"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0043223 -->

    <owl:Class rdf:about="&obo;GO_0043223">
        <rdfs:label rdf:datatype="&xsd;string">cytoplasmic SCF ubiquitin ligase complex</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="&obo;GO_0019005"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="&obo;BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="&obo;GO_0005737"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0043223</oboInOwl:id>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">cytoplasmic SCF complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">cytoplasmic Skp1/Cul1/F-box protein complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">cytoplasmic cullin complex</oboInOwl:hasExactSynonym>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:15571813</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:15688063</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0043223"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0043224 -->

    <owl:Class rdf:about="&obo;GO_0043224">
        <rdfs:label rdf:datatype="&xsd;string">nuclear SCF ubiquitin ligase complex</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="&obo;GO_0019005"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="&obo;BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="&obo;GO_0005634"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="&obo;GO_0000151"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0019005"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044428"/>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0043224</oboInOwl:id>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">nuclear SCF complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">nuclear Skp1/Cul1/F-box protein complex</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">nuclear cullin complex</oboInOwl:hasExactSynonym>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:15571813</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">PMID:15688063</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0043224"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0043226 -->

    <owl:Class rdf:about="&obo;GO_0043226">
        <rdfs:label rdf:datatype="&xsd;string">organelle</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0005575"/>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0043226</oboInOwl:id>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">NIF_Subcellular:sao1539965131</oboInOwl:hasDbXref>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.</obo:IAO_0000115>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">Wikipedia:Organelle</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_generic"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_pir"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:go_curators</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0043226"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0043227 -->

    <owl:Class rdf:about="&obo;GO_0043227">
        <rdfs:label rdf:datatype="&xsd;string">membrane-bounded organelle</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0043226"/>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0043227</oboInOwl:id>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">NIF_Subcellular:sao414196390</oboInOwl:hasDbXref>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.</obo:IAO_0000115>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">membrane-enclosed organelle</oboInOwl:hasExactSynonym>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:go_curators</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0043227"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0043229 -->

    <owl:Class rdf:about="&obo;GO_0043229">
        <rdfs:label rdf:datatype="&xsd;string">intracellular organelle</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0043226"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0044424"/>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0043229</oboInOwl:id>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.</obo:IAO_0000115>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_pir"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:go_curators</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0043229"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0043231 -->

    <owl:Class rdf:about="&obo;GO_0043231">
        <rdfs:label rdf:datatype="&xsd;string">intracellular membrane-bounded organelle</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0043227"/>
        <rdfs:subClassOf rdf:resource="&obo;GO_0043229"/>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0043231</oboInOwl:id>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.</obo:IAO_0000115>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">intracellular membrane-enclosed organelle</oboInOwl:hasExactSynonym>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_pir"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:go_curators</oboInOwl:hasDbXref>
        <owl:annotatedTarget rdf:datatype="&xsd;string">Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.</owl:annotatedTarget>
        <owl:annotatedSource rdf:resource="&obo;GO_0043231"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0043234 -->

    <owl:Class rdf:about="&obo;GO_0043234">
        <rdfs:label rdf:datatype="&xsd;string">protein complex</rdfs:label>
        <rdfs:subClassOf rdf:resource="&obo;GO_0032991"/>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0043234</oboInOwl:id>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">Wikipedia:Protein_complex</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym rdf:datatype="&xsd;string">protein-protein complex</oboInOwl:hasExactSynonym>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_generic"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#goslim_pir"/>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:go_curators</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0043234"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0044422 -->

    <owl:Class rdf:about="&obo;GO_0044422">
        <rdfs:label rdf:datatype="&xsd;string">organelle part</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="&obo;GO_0005575"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="&obo;BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="&obo;GO_0043226"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0044422</oboInOwl:id>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:jl</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0044422"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0044424 -->

    <owl:Class rdf:about="&obo;GO_0044424">
        <rdfs:label rdf:datatype="&xsd;string">intracellular part</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="&obo;GO_0005575"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="&obo;BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="&obo;GO_0005622"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0044424</oboInOwl:id>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:jl</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0044424"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0044425 -->

    <owl:Class rdf:about="&obo;GO_0044425">
        <rdfs:label rdf:datatype="&xsd;string">membrane part</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="&obo;GO_0005575"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="&obo;BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="&obo;GO_0016020"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0044425</oboInOwl:id>
        <oboInOwl:hasOBONamespace rdf:datatype="&xsd;string">cellular_component</oboInOwl:hasOBONamespace>
        <oboInOwl:inSubset rdf:resource="&obo;go#gosubset_prok"/>
    </owl:Class>
    <owl:Axiom>
        <owl:annotatedTarget rdf:datatype="&xsd;string">Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.</owl:annotatedTarget>
        <oboInOwl:hasDbXref rdf:datatype="&xsd;string">GOC:jl</oboInOwl:hasDbXref>
        <owl:annotatedSource rdf:resource="&obo;GO_0044425"/>
        <owl:annotatedProperty rdf:resource="&obo;IAO_0000115"/>
    </owl:Axiom>


    <!-- http://purl.obolibrary.org/obo/GO_0044428 -->

    <owl:Class rdf:about="&obo;GO_0044428">
        <rdfs:label rdf:datatype="&xsd;string">nuclear part</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="&obo;GO_0005575"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="&obo;BFO_0000050"/>
                        <owl:someValuesFrom rdf:resource="&obo;GO_0005634"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <obo:IAO_0000115 rdf:datatype="&xsd;string">Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.</obo:IAO_0000115>
        <oboInOwl:id rdf:datatype="&xsd;string">GO:0044428</oboInOwl:id>