diff --git a/rbc/errors.py b/rbc/errors.py
index 9b91b3fb..09606505 100644
--- a/rbc/errors.py
+++ b/rbc/errors.py
@@ -3,9 +3,18 @@
 """
 
 
-from rbc.utils import get_version
 from numba.core.errors import TypingError
 
+from rbc.utils import get_version
+
+
+class LLVMVersionMismatchError(Exception):
+    """
+    Raised when Numba and HeavyDB uses different LLVM version which is known to
+    be incompatible/problematic.
+    """
+    pass
+
 
 class HeavyDBServerError(Exception):
     """
@@ -55,5 +64,5 @@ class NumbaNotImplementedError(TypingError):
     class RequireLiteralValue(TypingError):
         pass
 else:
-    from numba.core.errors import NumbaTypeError, NumbaNotImplementedError, \
-                                  RequireLiteralValue  # noqa: F401
+    from numba.core.errors import RequireLiteralValue  # noqa: F401
+    from numba.core.errors import NumbaNotImplementedError, NumbaTypeError
diff --git a/rbc/irtools.py b/rbc/irtools.py
index 1c7c6070..8656fd1f 100644
--- a/rbc/irtools.py
+++ b/rbc/irtools.py
@@ -18,7 +18,7 @@
 from rbc.externals import stdio
 from rbc.nrt import create_nrt_functions
 
-from .errors import UnsupportedError
+from .errors import UnsupportedError, LLVMVersionMismatchError
 from .libfuncs import Library
 from .targetinfo import TargetInfo
 
@@ -146,6 +146,8 @@ def _get_host_cpu_features(self):
         # See https://github.com/xnd-project/rbc/issues/45
         remove_features = {
             (12, 12): [], (11, 11): [], (10, 10): [], (9, 9): [], (8, 8): [],
+            (14, 11): ['crc32', 'uintr', 'widekl', 'avxvnni', 'avx512fp16', 'kl',
+                       'hreset'],
             (11, 8): ['tsxldtrk', 'amx-tile', 'amx-bf16', 'serialize', 'amx-int8',
                       'avx512vp2intersect', 'tsxldtrk', 'amx-tile', 'amx-bf16',
                       'serialize', 'amx-int8', 'avx512vp2intersect', 'tsxldtrk',
@@ -224,7 +226,6 @@ def post_lowering(self, mod, library):
 # ---------------------------------------------------------------------------
 # Code generation methods
 
-
 @contextmanager
 def replace_numba_internals_hack():
     # Hackish solution to prevent numba from calling _ensure_finalize. See issue #87
@@ -438,6 +439,27 @@ def compile_to_LLVM(functions_and_signatures,
       LLVM module instance. To get the IR string, use `str(module)`.
 
     """
+    # check LLVM version before compiling to LLVM
+    server_llvm_version = target_info.llvm_version
+    client_llvm_version = llvm.llvm_version_info
+
+    if (server_llvm_version[0], client_llvm_version[0]) == (11, 14):
+        c_llvm = '.'.join(map(str, client_llvm_version))
+        s_llvm = '.'.join(map(str, server_llvm_version))
+        flag = 'RBC_DISABLE_LLVM_MISMATCH_ERROR'
+        msg = (f'The client LLVM version ({c_llvm}) is greater than the server '
+               f'LLVM version ({s_llvm}). This is known to be unsupported. '
+               'Please, downgrade to a previous release of Numba that uses the '
+               'same LLVM version as the HeavyDB server. For more information, '
+               'see the table below:\n\n'
+               'https://github.com/numba/llvmlite#compatibility\n'
+               'https://github.com/heavyai/heavydb#dependencies\n\n'
+               f'To disable this error, run RBC with {flag}=1 flag enabled.')
+
+        DISABLE_LLVM_MISMATCH_ERROR = int(os.environ.get(flag, False))
+        if not DISABLE_LLVM_MISMATCH_ERROR:
+            raise LLVMVersionMismatchError(msg)
+
     target_desc = registry.cpu_target
 
     typing_context = JITRemoteTypingContext()
diff --git a/rbc/tests/heavydb/test_heavydb.py b/rbc/tests/heavydb/test_heavydb.py
index eb48dfca..41b1bda4 100644
--- a/rbc/tests/heavydb/test_heavydb.py
+++ b/rbc/tests/heavydb/test_heavydb.py
@@ -1,10 +1,14 @@
-import os
 import itertools
-import pytest
+import os
+
+import llvmlite.binding as llvm
 import numpy as np
+import pytest
 
-from rbc.errors import UnsupportedError, HeavyDBServerError
-from rbc.tests import heavydb_fixture, assert_equal
+from rbc.errors import (HeavyDBServerError, LLVMVersionMismatchError,
+                        UnsupportedError)
+from rbc.targetinfo import TargetInfo
+from rbc.tests import assert_equal, heavydb_fixture
 from rbc.typesystem import Type
 
 rbc_heavydb = pytest.importorskip('rbc.heavydb')
@@ -872,3 +876,36 @@ def rbc_test_non_admin_user_udf(x):
     # clean up:
     heavydb.sql_execute(f'DROP DATABASE IF EXISTS {dbname};')
     heavydb.sql_execute(f'DROP USER IF EXISTS "{user}";')
+
+
+@pytest.mark.parametrize('kind', ('udf', 'udtf'))
+def test_numba_heavydb_llvm_mismatch(heavydb, kind):
+    heavydb.reset()
+
+    # only run this test on a specific environment
+    target_info = TargetInfo()
+    server_llvm_version = target_info.llvm_version
+    client_llvm_version = llvm.llvm_version_info
+
+    if (server_llvm_version[0], client_llvm_version[0]) != (11, 14):
+        c_llvm = '.'.join(map(str, client_llvm_version))
+        s_llvm = '.'.join(map(str, server_llvm_version))
+        msg = (f'Test requires server LLVM 14, got {s_llvm}. And client LLVM '
+               f'11, got {c_llvm}')
+        pytest.skip(msg)
+
+    if kind == 'udf':
+        @heavydb('int32(int32)')
+        def add(a):
+            return a + 1
+    else:
+        @heavydb('int32(TableFunctionManager, Column<int>, OutputColumn<int>)')
+        def column_copy(mgr, inp, out):
+            size = len(inp)
+            mgr.set_output_row_size(size)
+            for i in range(size):
+                out[i] = inp[i]
+            return size
+
+    with pytest.raises(LLVMVersionMismatchError):
+        heavydb.register()